美因基因年度报告2023

股份代號: 6667(於開曼群島註冊成立的有限公司) 2023年 度 報 告 2 689101930385788124128129131132134 1 528 97927 818 Third Floor, Century YardCricket Square, P.O. Box 902Grand Cayman, KY1-1103Cayman Islands 2 (1)20241 17(2)20237 21 401 6667 3485 www.megagenomics.cn Appleby Global Services (Cayman) Limited71 Fort StreetPO Box 500George TownGrand Cayman KY1-1106Cayman Islands 1617 20231231 2023 151.3202216.8%30.0202247.6163.720226.9 20243 26 20231231201619 2021123120202022610 202312319786 ••••• ••Septin9•RNF180/Septin9• •Plus•(i)(ii) IVD (i)(ii)ApoE(iii)BRCA1/BRCA2 (i)(ii)(iii)(iv)(v) ApoE ApoEqPCRApoEApoEApoEϵ4 2022531,2002024 qPCRMTHFR 20225NMPA2024 miRNA1,500 RT-qPCRNGSNGSLDT RT-qPCR2025 DNA 2023123131,500 qPCRNGS NGSLDT90% qPCR2025 DNA 2023123131,500 qPCRNGS NGSLDT90% qPCR2025 BRCA1/BRCA2 BRCA1/BRCA2PCR 20231231 1231 201620231231202215% 202312315058 65% IVDIVD IVDCROIVD 20231231 IVD CDMOCDMOIVDPCR CRO PCRqPCRNGSPCR IVDNMPAcfDNANMPAApoEIVDBRCA1/BRCA2 PCRqPCRNGSPCR50,000 880PCR2022 151.33.8%16.8%30.0202217.62023202247.6 3401,80054% 20231231151.32022145.75.63.8%16.8%20231231108.442.9 2023123188.38.0%57.331.064.4% 2023123158.4%2023123172.1%0.252.9%9.6 2023123130.019.9%202217.612.1%202347.6 202020300.8%11.6% 65%22.415%2023123197865058 3401,800100 IVD 20231231ApoE31,2002024 NMPA2024 31,500 BRCA1/BRCA2 20231231 cfDNA20231231 202212312023 •20231231108.434.5%68.3% •2023123142.934.1% 2022123164.01.6%202363.0 2022202312 3181.788.356.1%58.4% 2022123134.9202357.32022123143.3%202352.9% 2022123146.8202331.0 202212 3119.2202313.4 202212 3134.9202330.7 202212 3142.9202344.5 202212 3125.9202312 3111.6 202212312.520230.8 202212310.720231.1 6.120223.8 30.0202217.6 2022622 163.7 33.8 12.9 20221231399.829.6%20231231518.3 202212 31202312 3111.025.9 2023123122.620221.920.7 2320231231 2023123120221231 202312 3119.0%2022123112.4%6.6 (1)(2)(3) (1)(2)(3) 20231231 20231231 20231231 202312 3134.7202223.6 202312312022 202312 31229 202111 19202212 2927,272,000D.20221229 20231231 20214222022622 20226221811,961,800215.3153.420231231 1) 52201615202186 22 2004 1998320068 20103002577 20152 3202112 20161872612 20161120217300231 20175201912 20191201910 1993719998 2013720099 4820181202012 11202012 202132021422202186 2220076201212 20131 20171 4220171520201211202131820218616 20087201312 20141201612 20171 5202012202411620213182024116202132920214620239282021624 20066 2024117105(b) 442020112021862024117 21200311201262012720135201352018120181202011834425 20196 55202131820218 6 22200210 201510 20081 2015212 201712 6 20203 6 20147 45202186 15 201956006942022 20226000625202210600977 2002720077 46202186 152008920174201742015121520171025 2017112018630036420186201912 20186201912Crazy Maple Studio, Inc. 202011 20047201962820163.10(2) 43202186 1220119201532015720209 (1)(2)(3)(4)(5) 2006720118 38201731520218 10 1520087201562016620173 20056 2023721 43201972215 20089201778247 2017820195 2008720209 40201712199 620163 20163201712 20137 4020178117 20061220111 2011220177 20196 20231231 C1 20231231 20231231 12 12024117 22024117 202312316211 202312 31 C.5.1 2024117 20231231 3.13 20231231 20231231 (i) (ii) (iii) (iv) (v) 108 20231231 202312 31202212 312023630 20231231 20231231 20231231 20231231 757620231231 (i)(ii)(iii)(iv)(v) (i)(ii)(iii) •••18•• 20231231 A.2.1 20231231 (i)(ii)(iii) 20231231 20231231 202312311.2 2023721 3.28 202312313.2915 64 21 401 3485 ir@megagenomics.cn (a) (a)(b)(c)(d)(e)(f) (www.hkex.com.hk) (b) (c) (www.megagenomics.cn) (d) (e) www.tricoris.comis-enquiries@hk.tricorglobal.com2980 13331617 ir@megagenomics.cn401 (f) (g) ESG C2 20231120231231 ESGESGESGESG2022ESGESGESGESGESGESGESGESG ESGESGESG ESGESGESGESGESGESG 2023ESG2024326 1 1.1 20162023123119202112312020 50,000202312313401,800 1.2 1.3 ESGESGESG 1.4 ESG 1.5 19ESGESG ESGESG 2 2.1 2.1.1 2 DB11/501-2017II50 mg/m320230.36 mg/m320222.56 mg/m3 810.892022798.673.06 2024123120233.58 57.400.22 SOP-016-SYGL-2.0EHS 2024123120230.22 2.2 916.982022903.163.4620223.0018-25 2024123120233.46 28020222341.0620220.78 2024123120231.06 2.3 pH69(COD)500DB11/501-2017 2.4 2.4.1 TCFDESGESG 2.4.2 1. 2.26 3. 4. 6. 1)2)3)4) 7. 1) 2) 3 3.1 3.1.1 9416 2022 3.1.2 202398.1% 1.2.3.4.5.6.7. 3.1.3 202312312292022301 3.1.4 20231231849%202245% 8 3.2 EHSEHS 36 2022 3.2.1 1. 2. 3. 4. 2022 3.2.2 3.3 3.3.1 202311.521020229.25 130260 10 2,63920222,7831,82120222,015 3.4 2022 4 4.1 2012022127 4.2 (ISO15189:2012)352016182021 20222022 4.2.1 (CNAS)ISO15189:2012 21 4.2.2 HPV 314202244735202237400 4.3 4.3.1 (i) (ii)(iii)(iv)(v)(vi) (i)(ii)(iii) 4.3.2 4.3.3 4.4 20233215058PCRmiRNAqRT-PCR 202220222022 4.5 ESG 2022 5 5.1 3 20231231 20214222022622 2023123110181929 20231231151.32022145.75.63.8%16.8%20231231108.442.9 20231231