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Implementation manual Framework and toolkit forinfection prevention and Implementation manual Framework and toolkit for infection prevention and control outbreak preparedness, readiness and response: implementation manual ISBN 978-92-4-010561-4 (electronic version)ISBN 978-92-4-010562-1 (print version) © World Health Organization 2025 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0IGO licence(CCBY-NC-SA3.0IGO;https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the workis appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specificorganization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license yourwork under the same or equivalent Creative Commons licence. If you create a translation of this work, you should add the followingdisclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not Suggested citation.Framework and toolkit for infection prevention and control outbreak preparedness, readiness and response:implementation manual. Geneva: World Health Organization; 2025. Licence:CCBY-NC-SA3.0IGO. Sales, rights and licensing.To purchase WHO publications, seehttps://www.who.int/publications/book-orders. To submit requestsfor commercial use and queries on rights and licensing, seehttps://www.who.int/copyright. Third-party materials.If you wish to reuse material from this work that is attributed to a third party, such as tables, figures orimages, it is your responsibility to determine whether permission is needed for that reuse and to obtain permission from thecopyright holder. The risk of claims resulting from infringement of any third-party-owned component in the work rests solely with the General disclaimers.The designations employed and the presentation of the material in this publication do not imply the expressionof any opinion whatsoever on the part of WHO concerning the legal status of any country, territory, city or area or of its authorities, or The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommendedby WHO in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietaryproducts are distinguished by initial capital letters. All reasonable precautions have been taken by WHO to verify the information contained in this publication. However, the publishedmaterial is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation anduse of the material lies with the reader. In no event shall WHO be liable for damages arising from its use. Content vviiviiix1 AcknowledgementsAbbreviations Chapter 1. Introduction to the implementation manual 1.1 Background1.2 Objective Chapter 2. Phase 1: IPC outbreak preparedness 2.1 Introduction 2.2 Step by step of key actions and available tools for IPC preparedness A.Immediate priority: develop an IPC foundationB.Early priority: identify key personnel and partners Chapter 3. Phase 2: IPC outbreak readiness 3.1 Introduction 3.2 Step by step of key actions and available tools for IPC readiness A.Immediate priority: adapt existing tools for IPC in outbreaksB.Early priority: prepare key personnel and partnerships Chapter 4. Phase 3: IPC outbreak response 4.1 Introduction 4.2 Step by step of key actions and available tools for IPC response A.Immediate priority: activate existing and adapted tools for IPC based on outbreak contextB.Early priority: monitor for resurgence of cases Chapter 5 – Country examples and case studies 5.1 Introduction345.2 Country example number 1: Simulation of Hospital Preparation for Ebola Outbreak - Singapore345.3 Country example number 2: IPC National outbreak task force, training, and stakeholder’s network – Nigeria355.4 Country example number 3: Surge capacity and training – Yemen38 References Acknowledgements The World Health Organization (WHO) gratefully acknowledges the many individuals who contributed to the Overall coordination, writing and design of the document April Baller (Infection Prevention and Control (IPC) and Water, Sanitation and Hygiene (WASH) team lead, WHO HealthEmergencies Programme) coordinated and contributed to writing of the document; Luciana Cordeiro (School ofNursing, University of São Paulo, Brazil) led the literature review; Stacey Mearns (UK Public Health Rapid SupportTeam, United Kingdom of Great Britain and Northern Ireland) contributed to development of the document); MariaClara Padoveze (Consultant, WHO Health Emergencies Programme) led the writing of the document, contributed tothe literature review, and led the interviews and fo