2025年全球抗菌素耐药性人类健康研究议程报告

Global research agenda forantimicrobial resistance inhuman health Global research agenda for antimicrobial resistance in human health ISBN 978-92-4-010230-9 (electronic version)ISBN 978-92-4-010231-6 (print version) © World Health Organization 2024 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO;https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work fornon-commercial purposes, provided the work is appropriately cited, as indicated below.In any use of this work, there should be no suggestion that WHO endorses any specificorganization, products or services. The use of the WHO logo is not permitted. If youadapt the work, then you must license your work under the same or equivalent CreativeCommons licence. If you create a translation of this work, you should add the followingdisclaimer along with the suggested citation: “This translation was not created by theWorld Health Organization (WHO). WHO is not responsible for the content or accuracy ofthis translation. The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted inaccordance with the mediation rules of the World Intellectual Property Organization(http://www.wipo.int/amc/en/mediation/rules/). Suggested citation.Global research agenda for antimicrobial resistance in human health.Geneva: World Health Organization; 2024. Licence:CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.CIP data are available athttps://iris.who.int/. Sales, rights and licensing.To purchase WHO publications, seehttps://www.who.int/publications/book-orders. To submit requests for commercial use and queries on rightsand licensing, seehttps://www.who.int/copyright. Third-party materials.If you wish to reuse material from this work that is attributed to athird party, such as tables, figures or images, it is your responsibility to determine whetherpermission is needed for that reuse and to obtain permission from the copyright holder.The risk of claims resulting from infringement of any third-party-owned component in thework rests solely with the user. General disclaimers.The designations employed and the presentation of the materialin this publication do not imply the expression of any opinion whatsoever on the part ofWHO concerning the legal status of any country, territory, city or area or of its authorities,or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines onmaps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not implythat they are endorsed or recommended by WHO in preference to others of a similarnature that are not mentioned. Errors and omissions excepted, the names of proprietaryproducts are distinguished by initial capital letters. All reasonable precautions have been taken by WHO to verify the information contained inthis publication. However, the published material is being distributed without warranty ofany kind, either expressed or implied. The responsibility for the interpretation and use ofthe material lies with the reader. In no event shall WHO be liable for damages arising fromits use. Design and layout: Polygram/Gaelen Pinnock Contents Acknowledgements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .vAbbreviations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiiList of tables and figures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiiiGlossary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xivExecutive summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xvi 1.1 Background. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11.2 Purpose and scope of the research agenda. . . . . . . . . . . . . . . . . . . . . . . . . . . .21.3 Intended audience. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 2. Global research priorities for AMR in human health. . . . . . . . . . . . . . . . . . . . . .4 2.1 Overview. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .42.2 The 40 research priorities. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15 3. Further considerations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .64 3.1 Policy implications. . . . . . . . . . . . . . . . . . . . . . .