The NATO Science and Technology Organization (STO) has released a report titled "Science & Technology Trends 2023-2043 Across the Physical, Biological, and Information Domains." The report is based on research and analysis conducted by the STO, with support from NATO Allied Command Transformation (ACT) and the NATO Communications and Information Agency (NCIA). The report provides considered advice to NATO and Nations' leadership on significant S&T issues. The report is not an official opinion or position of NATO or individual governments, but it does provide insight into the future of science and technology in security and defense. The report is distributed free of charge for informational purposes and may be obtained on request from the NATO Office of the Chief Scientist. The sale and reproduction of the report for commercial purposes is prohibited.