昭衍新药2023中期报告

(A joint stock company incorporated in the People’s Republic of China with limited liability)Stock Code: 6127 2023 2 6 7 9 10 11 24 49 51 53 55 56 H 1617 5100176 3485 5100176 H6127A603127 15323203-3207 108 35A509100033 www.joinnlabs.com 2023 10.1230.27%1.9530.82%38.7 I. 2,500 II20,00012,000202322,0002024 Non-GLP (1) 2023GLPGLP AICNSMRI100%DDI (2) IITIII ADCPROTAC (3) 2023 NHP (4) CNASGLP 202338.7 2023132023 1. 2.3.IPSC4.2.416% II. 20236 301,012.120226 30776.930.3% 20236 30564.320226 30398.941.4% 20236 30447.844.2%20226 30377.948.6%20236 30JOINN LABORATORIES, CA Inc. 20236 3099.820226 30120.417.1%20226 3014.4 20236 30198.820226 30131.3 20236 3011.920226 308.245.0% 20236 30159.720226 30158.80.6%20236302022 20236 3056.920226 3025.5123.4% 20236 301.6820226 301.732.7%20236 302022 20236 3027.420226 3064.857.6% 20236 3023.5%20226 3014.9% 20226 30370.475.8%202363089.520226 3047.7%20236 308.8% •195.3 •183.0 20236303,040.5202212312,916.84.2% 202363021.5%2022123121.0% 20236 3020236 30115.92022151.3 20236 30 20236 30 2022 20236 9202220222023A2023H202220237 2120237 2533,998,630H180,245,794A749,888,699 20236 302,500 291.32022241.9 III. CRO IV. II20,00012,0002023 2019BiomereBiomere Biomere (i)(ii) 20236 30 13.1313.14 13.15 13.20 13.21 20236 30XV352 (1)A119,400,452A20236 3022.29%A53,375,701A20236 309.96%A172,776,15320236 3032.25%A (2)L (3)20236 30535,678,676450,682,100A84,996,576HA 20236 30XVXV78352 20236 30XV233365% 20236 30XV233365% 201820192020 (a) (b) 2020 (c) (d) 5% (e) A (f) 1%10% (g) 48 20182019202012 (h) 60 (i) 122436 (i)50%1224(ii)30%2436(iii)20%3648 20192020(i)50%1224(ii)50%2436 (j) 48 (k) (i)1A11(ii)20A20A20A (i)1A1150%(ii)20A20A20A50% (l) (1) (2)(3)(4)(5) (m) (1)(2)(3)(4)A(5)AAA(6)(7)(8)(9)(10)(11) 20236 30A (1)2018(i)50%201941920204 18(ii)30%2020 4 1920214 18(iii)20%20214 1920224 18(2)2019(i)50%2020 10 14202110 13(ii)30%2021 10 14202210 13(iii)20%20221014202310 13(3)2019(i)50%202181120228 10(ii)50%2022 8 1120238 10(4)2020(i)50%2021 8 312022830(ii)30%2022 8 3120238 30(iii)20%2023 8 3120248 30(5)48(6)(7)20183 920199 920206 2420207 1759.8762.8196.5395.42(8)20231 120182019202029,00140,9261,420,020(9)20236 302018201920201,420,020(10)201820192020 20236 30A (1)2018(i)50%2019 4 1920204 18(ii)30%2020 4 1920214 18(iii)20%2021 4 1920224 18(2)2019(i)50%2020 10 14202110 13(ii)30%2021 10 14202210 13(iii)20%2022 10 14202310 13(3)2019(i)50%2021 8 1120228 10(ii)50%2022 8 1120238 10(4)48(5)(6)20183 920199 920206 2459.8762.8196.53(7)20231 120182019(8)20236 3020182019(9)20182019 20221 19202211 182021A2021A2022A 20221 192021A2021A (a) 2021A (b) 2021AAA (c) AA2021AA (d) 2021A5052021A5% 2021A1142022A204 (e) 2021AA (f) 2021A675,400AA0.13% 10%2021 AA1% 2021A2022A124,00020236 300.023% (g) 2021A482021A24 482021A (h) 2021A20222022A2022H20221 2820221 28 (i) 2021A1224362021AA 2021A(i)40%12124(ii)30%24136(iii)30%36148 2021A(i)40%121(ii)30%241(iii)30%361 2022A(i)50%121(ii)30%241(iii)20%361 (j) 2021AA (k) 2021A(i) 2021A1A1150%(ii) 2021A20A20A20A50% 150% 20236 30 2021 AA 1.2021A(i)40%2023 3 2920243 28(ii)30%2024 3 2920253 28(iii)30%20253 2920263 28 (2)48 (3)20233 302021A2021A20234 21187,880AA20234 2055.9969 2021A2022A20236 300.013% 0.23%0.096% 2022H 20226 242022H (a) 2022H(i)(ii)(iii) (b) 2022HH (c) (d) 2022HH (e) 2022H600H H 2022H (f) 2022H (i)(ii)(iii) (g) 2022H2022H20226 24102022H9 (h)H 2022HH 2022H 2022HH2,409,500H80,900,0000.45% 20233 3020234 273,2932019A31,1082021A20237 61,884,805.2920233 30202342720237 3 HH2,409,50080,900,000 20236 30 20236 30 3.21 20236 302023630 20236 30 (i) 20236 3020234 27 (ii) 20236 30 (iii) 20236 30 (iv) 20236 30 20236 30II. H2021226202131940,800H20213 24H151.006,373.65,285.2 (i)2022 4 28(ii)20224 28787.9(i)(ii)(iii) 20236 30 20236 30 20236 30 20236 30 20236 30 20236 30 1. 20178 25A603127.SHH20212 266127.HK 2. 3420238 30 202320223 34 2022 202212 31 3. •17•8•12•12 4. (a) 4(b)15 20236 303,870202212 314,400 4. (b) • (i)(ii)(iii) • (i)(ii)(iii) • (i) 4. (b) 4. (b) (iii) 5. 6. (a) 6. (b) 7.65%2023160,2005%100% 6. (c) 8. (a) 90,627,00020226 30371,120,000 (b) 90,627,00020226 30371,120,000 (i)202211 172022A202220231 668,5002022A39.87 9. 95,048,00020226 30169,338,000 10. 10. (a) 10. (b) 20236 30 20236 3035130,00055 20236 3010%160,286,000202212 31185,860,000 12. 13. 20236 30339,397,00020226 30221,146,000 14. 15. (a) (b) 2145 18. 19. 20236 30 21. 20198 1520192019201920199 9201920191,124,000405,000201910 1448.11124.06 202062420192019175,00063,00020208 1194.77147.39 20207 1520202020202071720202,089,000202083194.771 20221 192022202120221 282021366,30020223 2983.97 21. 20226 242022H2022H2022HHH2023630 202211 1720222022A20231 668,5002022A39.87 20222022H (a) 21. (a) (i)50%30%20%(ii)50%50% 21. (b) 21. (b) 20199 920206 2420221 2838.4447.2212.91 (c) (i)50