摩根士丹利美股招股说明书(2026-06-10版)

Pricing Supplement No. 16,586 toRegistration Statement Nos. 333-293641; 333-293641-01Dated, 2026Rule 424(b)(2) PROSPECTUS Dated April 8, 2026PRODUCT SUPPLEMENT Dated April 8, 2026INDEX SUPPLEMENT Dated April 8, 2026TAX SUPPLEMENT Dated April 8, 2026 Morgan Stanley Finance LLC STRUCTURED INVESTMENTSOpportunities in U.S. Equities $ Digital S&P 500®Index-Linked Notes due Fully and Unconditionally Guaranteed by Morgan Stanley Principal at Risk Securities The notesare unsecured obligations of Morgan Stanley Finance LLC (“MSFL”) and are fully and unconditionallyguaranteed by Morgan Stanley. The notes will not bear interest.The amount that you will be paid on your notes on thestated maturity date (expected to be the second scheduled business day after the determination date) is based on theperformance of the S&P 500® Index as measured from the trade date to and including the determination date (expected to bebetween 14 and 16 months after the trade date). If the final underlier level on the determination date is greater than or equal to90% of the initial underlier level (which will be set on the trade date and may be higher or lower than the actual closing level of theunderlier on the trade date), you will receive an amount equal to the maximum settlement amount (expected to be between$1,104.50 and $1,122.90 for each $1,000 face amount of your notes).However, if the underlier declines by more than 10%from the initial underlier level, the return on your notes will be negative. You could lose your entire investment in thenotes.The notes are notes issued as part of MSFL’s Series A Global Medium-Term Notes program. All payments are subject to our credit risk. If we default on our obligations, you could lose some or all of yourinvestment. These notes are not secured obligations and you will not have any security interest in, or otherwise haveany access to, any underlying reference asset or assets. To determine your payment at maturity, we will calculate the underlier return, which is the percentage increase or decrease in thefinal underlier level from the initial underlier level. On the stated maturity date, for each $1,000 face amount of your notes, you willreceive an amount in cash equal to: ●if the underlier return isgreater thanorequal to-10% (the final underlier level is greater than or equal to 90% of the initialunderlier level), the maximum settlement amount of $1,104.50 to $1,122.90 per note, or 110.45% to 112.29% of the faceamount (the actual maximum settlement amount will be determined on the trade date); or●if the underlier return isless than-10% (the final underlier level is less than 90% of the initial underlier level), thesumof(i)$1,000plus(ii)theproductof (a)$1,000times(b)approximately 1.1111times(c)thesumof the underlier returnplus10%.Under these circumstances, you will lose some or all of your investment. You should read the additional disclosure herein so that you may better understand the terms and risks of your investment. The estimated value on the trade date will be approximately $992.30 per note, or within $15.00 of that estimate.See “Estimated Value” on page 2. Per note Total (1)Morgan Stanley & Co. LLC (“MS & Co.”) will sell all of the notes that it purchases from us to an unaffiliated dealer at the original issue price of100.00%, or $1,000 per face amount of notes. Such dealer will sell the notes to investors at the same price without a discount or commission.Investors that purchase and hold the notes in fee-based accounts may be charged fees based on the amount of assets held in those accounts,including the notes. For more information, see “Additional Information About the Notes—Supplemental information regarding plan of distribution;conflicts of interest.”(2)See “Additional Information About the Notes—Use of proceeds and hedging” beginning on page 18. The notes involve risks not associated with an investment in ordinary debt securities. See “Risk Factors” beginning on page The Securities and Exchange Commission and state securities regulators have not approved or disapproved these notes, or determined if thisdocument or the accompanying product supplement, index supplement, tax supplement and prospectus is truthful or complete. Anyrepresentation to the contrary is a criminal offense. The notes are not deposits or savings accounts and are not insured by the Federal Deposit Insurance Corporation or any other governmentalagency or instrumentality, nor are they obligations of, or guaranteed by, a bank. You should read this document together with the related product supplement, index supplement, tax supplement and prospectus, each ofwhich can be accessed via the hyperlinks below. Please also see “Terms” on page 3 and “Additional Information About the Notes” on page 18. About Your Prospectus The notes are notes issued as part of MSFL’s Series A Global Medium-Term Notes program. This prospectus includesthis preliminary pricing supplement and the accompanying documents listed