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*Listed, not for trading, but only in connection with the listing of the applicable Registrant’s American Depositary Shares issued in respect thereof.Securities registered or to be registered pursuant to Section12(g)of the Act: None Indicate the number of outstanding shares of each of the issuer’s classes of capital or common stock as of December31, 2025: Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule405 of the Securities Act.Yes☑No Yes☐No☑Indicate by check mark whether the registrant (1)has filed all reports required to be filed by Section13 or 15(d)of the Securities Exchange Act of 1934 during the preceding 12months (or for such shorter Yes☑No☐Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule405 of Regulation S-T during the preceding 12months (or for such shorter period that the registrant was required to submit such files). Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or an emerging growth company. See definition of “accelerated filer,” “large acceleratedfiler” and “emerging growth company” in Rule12b-2 of the Exchange Act. Non-accelerated filer☐Emerging growth company☐ If an emerging growth company that prepares its financial statements in accordance with U.S. GAAP, indicate by check mark if the registrant has elected not to use the extended transition period forcomplying with any new or revised financial accounting standards† provided pursuant to Section13(a)of the Exchange Act. † The term “new or revised financial accounting standard” refers to any update issued by the Financial Accounting Standards Board to its Accounting Standards Codification after April5, 2012. If securities are registered pursuant to Section 12(b) of the Act, indicate by check mark whether the financial statements of the registrant included in the filing reflect the correction of an error to previouslyissued financial statements. TABLE OF CONTENTS PageGENERAL5SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS6PART 18ITEM 1:IDENTITY OF DIRECTORS, SENIOR MANAGEMENT AND ADVISERSN/AITEM 2:OFFER STATISTICS AND EXPECTED TIMETABLEN/AITEM 3:KEY INFORMATION8Risk Factors8ITEM 4:INFORMATION ON THE GROUP12Business Overview12Organisational Structure13History and Development14Property, Plant and Equipment15Intellectual Property15Government Regulation15Climate Change16ITEM 4A: UNRESOLVED STAFF COMMENTSN/AITEM 5:OPERATING AND FINANCIAL REVIEW AND PROSPECTS17Operating Results17Liquidity and Capital Resources26Short-Term Debt28Trend Information30Research and Development30ITEM 6:DIRECTORS, SENIOR MANAGEMENT AND EMPLOYEES31Directors31Senior Management32Compensation32Share Ownership32Board Practices38Employees39ITEM 7:MAJOR SHAREHOLDERS AND RELATED PARTY TRANSACTIONS40Major Shareholders40Related Party Transactions40ITEM 8:FINANCIAL INFORMATION41Financial Statements41Dividend Policy41Legal Proceedings41ITEM 9:THE OFFER AND LISTING42Trading Markets42ITEM 10: ADDITIONAL INFORMATION43Articles of Association43Exchange Controls47Taxation48Documents on Display50Annual Report to Security Holders50ITEM 11:QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK51ITEM 12:DESCRIPTION OF SECURITIES OTHER THAN EQUITY SECURITIES54PART II55ITEM 13: DEFAULTS, DIVIDEND ARREARAGES AND DELINQUENCIESN/AITEM 14:MATERIAL MODIFICATIONS TO THE RIGHTS OF SECURITY HOLDERS AND USE OFPROCEEDSN/AITEM 15: CONTROLS AND PROCEDURES55 Report of Independent Registered Public Accounting Firm56ITEM16A:AUDIT COMMITTEE FINANCIAL EXPERT58ITEM16B:CODES OF ETHICS58ITEM16C:PRINCIPAL ACCOUNTANT FEES AND SERVICES58ITEM16D:EXEMPTIONS FROM THE LISTING STANDARDS FOR AUDIT COMMITTEESN/AITEM16E:PURCHASES OF EQUITY SECURITIES BY THE ISSUER AND AFFILIATED PURCHASERS59ITEM16F:CHANGE IN REGISTRANT’S CERTIFYING ACCOUNTANTN/AITEM16G:CORPORATE GOVERNANCE60ITEM16H:MINE SAFETY DISCLOSUREN/AITEM 16I:DISCLOSURE REGARDING FOREIGN JURISDICTIONS THAT PREVENT INSPECTIONSN/AITEM 16J:INSIDER TRADING POLICIES60ITEM16K:CYBERSECURITY61PART IIIF-1ITEM 17: FINANCIAL STATEMENTS*F-1ITEM 18: FINANCIAL STATEMENTSF-1Report of Independent Registered Public Accounting FirmF-2Glossary of TermsS-1ITEM 19: EXHIBITSS-3*The registrant has responded to Item18 in lieu of responding to this Item. THIS PAGE INTENTIONALLY BLANK GENERAL RELX PLC is a public limited company, and owns all of the Group. As used in this Annual Report on Form20-F, the terms “Group”, “RELX”, “we”, “our” or “us” refercollectively to RELX PLC and its subsidiaries, associates and joint ventures. Additional terms are defined in theGlossary of Terms on pagesS-1 and S-2. In this Annual Report on Form20-F, references to US dollars, $ and ¢ are to US currency; references tosterling, £, pound sterling, pence or p are to UKcurrency; references to euro and €are to the currency of the EuropeanEconomic and Monetary Union. Statements regardi