2025年被忽视热带病全球报告：执行摘要

Global report onneglected tropicaldiseases2025 NomaOnchocerciasisRabiesScabies and otherectoparasitoses Executive summary In 2025, the WHO Global Neglected Tropical DiseasesProgramme marks 20 years of action and data. Sinceits establishment in 2005, a concerted effort involvingpharmaceutical manufacturers, development partners, Overall performance This report presents progress made in 2023–2024 towardsthe 2030 targets set inEnding the neglect to attain theSustainable Development Goals: a road map for neglectedtropical diseases 2021–2030(the road map), including several In 2023, an estimated 1.495 billion people requiredinterventions against NTDs, 122 million fewer than in 2022and a 32% decrease from the 2010 baseline. Between 2015and 2021, the disease burden dropped from 17.2 million to14.1 million DALYs, while NTD-related deaths decreased from •Progress on all overarching, cross-cutting and disease-specific indicators, milestones and targets. •Analysis of disease burden in terms of disability-adjusted life years (DALYs), prevalence and mortality, aswell as numbers of people affected by NTDs, detectedand treated.•New perspectives on the financial risk associatedwith NTDs, highlighting their impoverishing effects onaffected populations.•A detailed review of four thematic areas – diagnostics,monitoring and evaluation, access and logistics, andadvocacy and funding – enabled by the Gap Assessment In 2023, 867.1 million people were treated for at least oneNTD, 99% of whom received preventive chemotherapy. In 2024, WHO acknowledged seven countries for eliminatingan NTD (Brazil and Timor-Leste for lymphatic filariasis; Chadfor the gambiense form of human African trypanosomiasis;India, Pakistan and Viet Nam for trachoma; and Jordan for •Analysis of official development assistance for NTDs in thecontext of a constrained and evolving financial landscape. Diseases targeted for elimination asa public health problem Notable improvements were observed across severalcross-cutting indicators, including enhanced integrationin the implementation of preventive chemotherapy,as reflected by the improvement in the integratedtreatment coverage index. Additional progress wasregistered in the broader adoption of integratedstrategies for skin-related NTDs (skin-NTDs), the By the end of 2024, eight countries (Argentina, Brazil,Chile, Colombia, Paraguay, Peru, Plurinational State ofBolivia and Uruguay) had interrupted domiciliary vectortransmission ofChagas diseasein their entire national In 2023, four countries (Ethiopia, Malawi, UnitedRepublic of Tanzania and Zambia) reported 24 cases ofrhodesiense human African trypanosomiasis, a Although the number of cases ofvisceral leishmaniasishas remained stable over the past 4years, a major decline has occurred since 2014, driven In 2023, coverage of MDA forlymphatic filariasisreturned to pre-COVID-19 levels, aided in part by areduction of 137 million in the number of people Diseases targeted for eradication In 2024, 15 human cases ofdracunculiasis (Guinea-worm disease)were reported from only twocountries (Chad and South Sudan); however, animal Improved data collection onrabiesled to a significantincrease in the number of reported deaths in 2022– As of the end of 2024, 16 countries across three WHOregions remained endemic foryaws. Additionally,82 countries previously classified as endemic require The number of people requiring preventivechemotherapy forschistosomiasisdecreasedby 11.3 million between 2022 and 2023. However, In a significant step forward, the process to establish ajoint commission for certification of both dracunculiasis Progress in the treatment ofsoil-transmitted helminthiasesremained stable. Mass treatment forthis group of diseases continues to represent one of theworld’s largest public health interventions, reaching over457 million people in 2023. In 2024, WHO published its Diseases targeted for elimination(interruption of transmission) In 2023, 10 countries reported 675 cases ofgambiensehuman African trypanosomiasisto WHO. A total of24 countries remain endemic, while seven have beenvalidated as having eliminated the disease as a public In 2024, three countries (India, Pakistan and Viet Nam)were validated by WHO for eliminatingtrachomaas apublic health problem. The number of people requiringinterventions against this disease declined to 114 million The same year, 184 countries, territories and areasreportedleprosydata to WHO, one of the mostcomprehensive reporting achievements among all NTDs;among these, 56 countries reported zero cases. In 2024, Diseases targeted for control Diagnostic capacity forBuruli ulceris beingstrengthened globally, as reflected in the growingproportion of laboratory-confirmed cases; however, Also in 2024, several countries advanced towardsstopping mass drug administration (MDA) for onchocerciasisand transitioning to post-treatmentsurveillance. In 2023, a record 172 million people weretreated with ivermectin for th