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2025 Series H 6.25%Junior Subordinated Debenturesdue 2085 We are offering $600,000,000 of our 2025 Series H 6.25% Junior Subordinated Debentures due 2085 (“junior subordinated debentures”). We willpay interest on the junior subordinated debentures quarterly on January1, April1, July1, and October1 of each year, beginning on January1, 2026 atthe rate of 6.25% per year. So long as no event of default has occurred and is continuing, we may defer interest payments on one or more occasions for up to 40 consecutivequarterly periods, as described in this prospectus supplement. Any deferred interest payments will bear additional interest at the rate of 6.25% per year,to the extent legally permitted. The junior subordinated debentures will mature on October1, 2085. The junior subordinated debentures will be issued in denominations of $25 and integral multiples thereof. We may redeem the junior subordinated debentures at our option, at the times and at the redemption prices described in this prospectussupplement. The junior subordinated debentures will be unsecured and will rank subordinate and junior in right of payment to all of our current andfuture senior indebtedness. The junior subordinated debentures will rank equal to any other junior subordinated debentures that we have issued or mayissue. We will apply for the listing of the junior subordinated debentures on the New York Stock Exchange. If approved for listing, trading on the NewYork Stock Exchange is expected to commence within 30 days after the junior subordinated debentures are first issued. Investment in the junior subordinated debentures involves risks. You should read carefully this prospectussupplement and the accompanying prospectus, including the section entitled “Risk Factors” that begins on pageS-8ofthis prospectus supplement, which describes some of these risks. Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities ordetermined if this prospectus supplement or the prospectus to which it relates is truthful or complete. Any representation to the contrary is acriminal offense. (1)An underwriting discount of $0.7875 per junior subordinated debenture sold in this offering (or up to $18,900,000 for all junior subordinateddebentures) will be deducted from the proceeds paid to DTE Energy Company by the underwriters. However, the discount will be $0.2500 perjunior subordinated debenture for sales to institutions. As a result of sales to certain institutions, the total underwriting discount and the totalproceeds to DTE Energy Company (after deducting such discount) will equal $8,677,709 and $591,322,291, respectively. Interest on the junior subordinated debentures will accrue from September 17, 2025. Purchasers of junior subordinated debentures must payaccrued interest if settlement occurs after that date. Delivery of the junior subordinated debentures will be made in book-entry form only through The Depository Trust Company on or aboutSeptember 17, 2025. Joint Book-Running Managers WellsFargoSecurities BofASecurities J.P.Morgan Co-Managers HuntingtonCapitalMarkets ComericaSecurities The date of this prospectus supplement is September 8, 2025. Table of Contents This prospectus supplement and the accompanying prospectus and any free writing prospectus that we file with the Securities and ExchangeCommission (“SEC”) contain and incorporate by reference information you should consider when making your investment decision. We have not, andthe underwriters have not, authorized any person to provide you with different information. If anyone provides you with different or inconsistentinformation, you should not rely on it. We are not, and the underwriters are not, making an offer to sell these junior subordinated debentures in anyjurisdiction where the offer or sale is not permitted. You should assume that the information appearing in this prospectus supplement or theaccompanying prospectus or any document incorporated by reference is accurate only as of its date. DTE Energy’s business, financial condition, resultsof operations and prospects may have changed since such date. To the extent that the information in the prospectus supplement differs from theinformation in the prospectus, you should rely on the information in the prospectus supplement. References in this prospectus supplement to “DTE Energy,” “we,” “us,” or “our” refer to DTE Energy Company and its consolidated subsidiaries. TABLE OF CONTENTS Prospectus Supplement Where You Can Find More InformationCautionary Statements Regarding Forward-Looking StatementsProspectus Supplement SummaryRisk FactorsUse of ProceedsDescription of Junior Subordinated DebenturesMaterial U.S. Federal Income Tax ConsiderationsERISA ConsiderationsUnderwriting (Conflict of Interest)Legal MattersExperts Prospectus About This ProspectusRisk FactorsCautionary Statements Regarding Forward-Looking StatementsDTE Energy CompanyUse of