无症状性传播感染管理指南

Guidelines for themanagement ofasymptomatic sexuallytransmitted infections Guidelines for the management of asymptomatic sexually transmitted infectionsISBN 978-92-4-010490-7 (electronic version)ISBN 978-92-4-010491-4 (print version)© World Health Organization 2025Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo).Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes,provided the work is appropriately cited, as indicated below. In any use of this work, there should be nosuggestion that WHO endorses any specific organization, products or services. The use of the WHO logo isnot permitted. If you adapt the work, then you must license your work under the same or equivalent CreativeCommons licence. If you create a translation of this work, you should add the following disclaimer along withthe suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is notresponsible for the content or accuracy of this translation. The original English edition shall be the binding andauthentic edition”.Any mediation relating to disputes arising under the licence shall be conducted in accordance with themediation rules of the World Intellectual Property Organization (http://www.wipo.int/amc/en/mediation/rules/).Suggested citation.Guidelines for the management of asymptomatic sexually transmitted infections. Geneva:World Health Organization; 2025. Licence: CC BY-NC-SA 3.0 IGO.Cataloguing-in-Publication (CIP) data.CIP data are available at https://iris.who.int/.Sales, rights and licensing.To purchase WHO publications, see https://www.who.int/publications/book-orders. To submit requests for commercial use and queries on rights and licensing, see https://www.who.int/copyright.Third-party materials.If you wish to reuse material from this work that is attributed to a third party, such astables, figures or images, it is your responsibility to determine whether permission is needed for that reuse andto obtain permission from the copyright holder. The risk of claims resulting from infringement of any third-party-owned component in the work rests solely with the user.General disclaimers.The designations employed and the presentation of the material in this publicationdo not imply the expression of any opinion whatsoever on the part of WHO concerning the legal status of anycountry, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.Dotted and dashed lines on maps represent approximate border lines for which there may not yet be fullagreement.The mention of specific companies or of certain manufacturers’ products does not imply that they areendorsed or recommended by WHO in preference to others of a similar nature that are not mentioned. Errorsand omissions excepted, the names of proprietary products are distinguished by initial capital letters.All reasonable precautions have been taken by WHO to verify the information contained in this publication.However, the published material is being distributed without warranty of any kind, either expressed orimplied. The responsibility for the interpretation and use of the material lies with the reader. In no event shallWHO be liable for damages arising from its use.Design and layout: Studio FFFOG. AcknowledgementsExecutive summarySummary of recommendations1. Introduction1.1 Epidemiology and global targets1.2 Rationale for new and updated recommendations1.3 Objectives1.4 Target audience1.5 Guiding principles1.6 Structure of the guidelines2. Methods2.1 Overview2.2 Roles of groups involved in developing the guidelines2.3 Scope and questions2.4 Reviews of the evidence and modelling to inform guidelines2.5 Assessment and presentation of the evidence2.6 Making recommendations2.7 Managing conflicts of interest3. Updated and new recommendations3.1 Pregnant women3.2 Adolescents and young people3.3 Sex workers3.4 Men who have sex with men3.5 Research needs4 Other recommendations related to asymptomatic screening of STIs4.1 SyphilisContents vviiviii123344567789910111213141516171819 Guidelines for the management of asymptomatic sexually transmitted infections5. Implementation considerations for the management of asymptomatic STIs5.1 Definition of screening5.2 Rationale and objectives for establishing screening programmes for asymptomatic STIs5.3 Ethical considerations5.4 Selecting diagnostic tests for screening asymptomatic STIs5.5 Acceptable performance characteristics of a screening test5.6 Treatment, antibiotic consumption and preparedness for the screening programme5.7 Screening as an integrated prevention intervention5.8 Ensuring early and effective treatment5.9 STI services for key populations, adolescents and young people5.10 Antenatal screening for pregnant women6. Disseminating and updating the guidelin