2025中国医药CDMO行业发展洞察蓝皮书

CDMOCDMOCDMOCDMOCDMOCGTADCCDMOCDMOADCCDMOAbstract CDMOCDMOCDMO2025CDMOCDMOCDMOCDMOCDMOCDMOMAHGMPAI→→→CDMOCDMO+CDMOBiopharmaCDMOBiotechINDCDMO+CDMOAICDMOCDMOCRDMO+ CDMOCDMO——CDMO——CDMO——CDMO——ADC CDMO——CGT CDMOCDMO——CDMO————CDMO——CDMO CDMO•CDMO--------------------------------•CDMO--------------------------------•CDMO--------------------------------CDMO•--------------------------------•--------------------------------•CDMO--------------------------------•--------------------------------•--------------------------------•--------------------------------•--------------------------------•--------------------------------•CDMO•CDMOCDMO•CDMO•CDMO 6791415161721252934--------------------------------40--------------------------------42--------------------------------44--------------------------------47 ——CDMO——CDMOCDMO •CDMO•CDMOCDMO•CDMO•CDMO••••••••••••••• --------------------------------51--------------------------------53--------------------------------56--------------------------------58--------------------------------60--------------------------------62--------------------------------64--------------------------------66--------------------------------66--------------------------------67--------------------------------68--------------------------------70--------------------------------72--------------------------------74--------------------------------76--------------------------------78--------------------------------78 CDMO ◼CDMOCDMO◼CDMOCDMOCDMOCDMOCDMOCDMOCDMOBiopharmaBiopharmaBiopharmaBiotechBiotech CDMOCDMOCDMOCDMOBiopharmaBiotechCDMOCDMO01Biopharma02BiotechCDMO 1980-20152016-2020◼CDMOCDMO1980-20152016-20202030CDMOGMP2015CDMOEHS201860%MNC•1989•199220131.27.5•1985CDMOCRO/CDMO2007CDMOMAH20158CDMOGMP 20212023◼GMP◼•20162019MAH•2017•201730%-60%50%CDMO19972011152000MAH API/BiotechCDMO20232024CDMO ◼CDMO2021-2023CDMOCDMO20202023CGTCDMO2023CDMOCDMOPETTM2021295.5 294.6 141.0 179.9 155.3CDMOCGTADCCDMOADC13200ADCLinker-Payload2.2202462%STEMCDMOCDMOCDMO34.7%CDMOCDMO2024-CDMOAICDMOCDMOADCCGTCDMOCGTCDMO2017CAR-TCDMO201820191CDMOFDA/EUGMP  ◼151227.72.2CCGTCDMO2023CDMOCDMO1,1792020STEM700CDMO202419,19250%◼CDMOADC2020CDMOADC2015CGT20132018CDMO2019NMPACGTCDMO2019FDA/EMA ◼CDMO◼CDMO5,19176%2,000MAHCDMO◼CDMOCDMOCDMO01CDMOBiotechCDMO02+03CDMOCDMOTOP1023.240.258.223.721.830.78.618.72019202020212024 201845.6%CDMOROICDMOCDMOCDMO72.593.548.153.1115.158.681.620222023wind, ◼CDMOCDMO20193,3762024CDMO202313,24514,72320,6945.0%CDMOCDMO3,3763,8454,3922019202020212019-2024Comirnaty40.341ComirnatyHumira20.694HumiraSpikevax17.675KeytrudaKeytruda17.186PaxlovidRevlimid12.891SpikevaxEliquis10.762EliquisImbruvica9.777BiktarvyEylea9.235RevlimidStelara9.134StelaraBiktarvy8.624EyleaTOP101,244.91,326.1156.3168.9202120221,401.21,495.0 insights◼5,003◼201920304,3444,5445,003202220232024/37.806Keytruda25.01121.237Humira14.40420.937Ozempic13.91718.933Eliquis12.20618.435Biktarvy11.8511.789Dupixent11.58810.39Comirnaty11.229.978Stelara10.8589.723Jardiance10.759.639Opdivo10.0351,340.5131.820231,472.3TOP10 ◼CDMOcompound2013201920232010,7576.8%CDMO1.31.41.51.51.82.2201320142015201620172018CDMOCDMOCDMOFarevaSACDMOSyngene3,700EmergentBioSolutions2200CDMOSennChemicalsCDMOCDMOJSR2025478.450%CDMOCDMO•2019Catalent•2023ThermoFisherGibcoCDMOCDMO2020GMP202111335P54 ◼132023237,15510.7%CDMO2.42.42.02.32019202020212022◼CatalentThermo Fisher LonzaCDMO20253GranulesIndiaCDMO1/3GibcocGMP202023 2.32023202511830-+2024 ◼CDMOFirst-in-class FIC1986FDAFirst-in-class FICCDMOCDMOCDMOCGTADCCDMO2021 vs 202415120157221708997352911451840262511635926121531371272952024202120242021202120242021202454CDMO&998202312ADCCGT72023192023182023ADC252023142022 ◼CDMOPROTACOKT320212024/ADCCDMO◼732236214307273971744104731132615202147202420212021202420241First-in-classFast-followerMe-too/ADCCDMO34CDMO7,021202354520235972023362023 33313420242021 CDMO CDMOCDMO2022CDMOCDMOCDMO2018-2033E2018-202312.3%2023-2028E16.1%CDMOCDMO20182023CDMO12.3%CDMO20331,6843,38549.055.463.277.279.787.0100.9118.9201920202021202220232024E2025E 2026E 2027E 2028E 2029E 2030E 2031E 2032E 2033E 20222,415202246.5%CDMOCDMO2022CDMO7722028-2033E15.0%◼446797CDMOCDMO202844.6141.6168.4197.3228.2261.4298.0338.52018 CDMO20231742023MAHCDMO2018-2033E2018-202339.9%2023-2028E19.4%CDMOCDMOCDMOCDMOCDMOMAHMAHCDMOCDMO2023CDMO39.9%20335,369CDMO201820235.1%15.3%22.931.747.382.085.995.6113.3137.02018201920202021202220232024E2025E 2026E 2027E 2028E 2029E 2030E 2031E 2032E 2033E2022202330196046.6%55.8% CDMO2018202330111.5%202330146.6%202355.8%202346.6%2028-2033E20.8%◼ADCCDMO2019+201816085920282,084CDMO16.0169.1208.4256.5313.0378.8452.8536.9 CDMOCDMOCDMOCDMOCDMOLonzaBoehringerIngelheimCDMO••CDMO••-CDMO•OXGENECDMO•China+1”CDMOCXOIPSODivi’sLaboratoriesPiramalPharmaSolutions •••••• •CGT•CDMOCDMO•AGCJSRCDMOCatalentThermoFisherScientificCramlington ——CDMOCDERNMEs2023CDER38NMEs29NCEs2019-2030E286.4353.8732.51,038.01,118.51,336.9201920232030E1,324.51,472.32,069.4FDA CDER2000-202326155312004218200541820061620073212008